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Cruise South America

686 cruises
South America: Brazil
Santos Itinerary South America
from $600
price per person Taxes included
See the cruise Book
MSC Preziosa | Dec. 7, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Angra Dos Reis,
3. Buzios,
4. Santos
South America: Brazil
Santos Itinerary South America
from $616
price per person Taxes included
See the cruise Book
MSC Sinfonia | Dec. 5, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
South America: Brazil
Santos Itinerary South America
from $616
price per person Taxes included
See the cruise Book
MSC Sinfonia | Nov. 28, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
South America: Brazil
Santos Itinerary South America
from $616
price per person Taxes included
See the cruise Book
MSC Sinfonia | Dec. 12, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
sold out
Brazil
Santos Itinerary South America
from $616
price per person Taxes included
MSC Lirica | Dec. 12, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
sold out
Brazil
Santos Itinerary South America
from $616
price per person Taxes included
MSC Lirica | Dec. 5, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
sold out
Brazil
Santos Itinerary South America
from $616
price per person Taxes included
MSC Lirica | Nov. 28, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Buzios,
3. navigation,
4. Santos
South America: Brazil
Santos Itinerary South America
from $649
price per person Taxes included
See the cruise Book
MSC Sinfonia | Nov. 25, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. Ilha Grande,
3. navigation,
4. Santos
sold out
Brazil
Santos Itinerary South America
from $657
price per person Taxes included
MSC Lirica | Dec. 8, 2025
Duration: 4 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. navigation,
3. Buzios,
4. Ilha Grande,
5. Santos
sold out
Brazil
Santos Itinerary South America
from $674
price per person Taxes included
Costa Diadema | Dec. 5, 2025
Duration: 3 nights
Departure from: Santos Landing: Santos
Itinerary:
1. Santos,
2. navigation,
3. Itajai,
4. Santos
686 cruises

Departure calendar

Have you already decided when will be your next cruise with destination South America? Whatever month you choose will be the perfect opportunity to set off to discover the local wonders

  • 2026
  • 2027
  • 2028
November 2025 December 2025
January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026
January 2027 February 2027 March 2027 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027
January 2028 February 2028 March 2028

Reviews South America

13 reviews with average 7.62

Discover the impressions and ratings of other cruisers about cruises South America. Evaluate the experiences of others and make the right choice

star star star star 8/10

Roberto Greco Saturday, December 30, 2023
star star star star star 10/10

Giovanni Emanuele Fernandez Thursday, December 28, 2023
star star star star 7/10

Vincenzo Pascolo Monday, April 10, 2023
star star star star 8/10

Vito Fernando Gautieri Friday, February 10, 2023
star 1/10

vittorio Wednesday, February 8, 2023
star star 4/10

Stefania Bonfante Tuesday, February 7, 2023
star star star star star 10/10

Angela Donati Saturday, January 21, 2023
star star star star 8/10

Stefano Dionisi Thursday, January 12, 2023
star 1/10

Agatino Massimo Ventimiglia Tuesday, January 10, 2023
star 1/10

Giovanni Paternò Wednesday, December 14, 2022

Ports of departure

Get ready to experience your sea holiday with destination South America aboard the best cruise ships operating from the main ports of the region

  • Other ports
Auckland Images of Auckland Balboa Images of Balboa Baltra Images of Baltra Bridgetown Images of Bridgetown Buenos Aires Images of Buenos Aires Colon Images of Colon Fort Lauderdale Images of Fort Lauderdale Halifax Images of Halifax
Itajai King George Island Lima Los Angeles Maceio Miami Montevideo New York Puerto Baquerizo Moreno Puerto Williams Punta Arenas Rio de Janeiro Saint Johns Salvador San Antonio San Juan Santiago Santos Savona Seattle Singapore Southampton Ushuaia Valparaiso Vancouver Whittier

the ships

Get ready to experience your sea holiday aboard the best cruise ships operating from the main ports of the South America area

  • Other ships
MSC Armonia Images of MSC Armonia MSC Fantasia Images of MSC Fantasia MSC Preziosa Images of MSC Preziosa MSC Seaview Images of MSC Seaview MSC Sinfonia Images of MSC Sinfonia Costa Diadema Images of Costa Diadema Costa Favolosa Images of Costa Favolosa Costa Serena Images of Costa Serena
Serenade Of The Seas Norwegian Jade Celebrity Equinox Celebrity Flora Oosterdam Volendam Zaandam Zuiderdam Coral Princess Discovery Princess Grand Princess Majestic Princess Sapphire Princess Explora II Queen Anne Azamara Journey Azamara Quest Silver Cloud Silver Endeavour Silver Nova Silver Origin Silver Ray Silver Wind Star Pride Insignia Marina Sirena Vista Seabourn Venture Seven Seas Grandeur Seven Seas Mariner Seven Seas Splendor Seven Seas Voyager Hanseatic Inspiration

The countries to visit

Immerse yourself fully in the local culture and get ready to discover the wonders and gastronomy of the destination South America, one of the most loved and visited in the world.

Antigua and Barbuda Images of Antigua and Barbuda Argentina Images of Argentina Brazil Images of Brazil Ecuador Images of Ecuador Panama Images of Panama United States Images of United States Uruguay Images of Uruguay